Opana Addiction and Choosing the Best Inpatient Rehab Center

Photo of Lisa Conatser Lisa Conatser Info icon
Calendar icon Last Updated: 04/8/2022

Reading Time: 7 minutes

Opana is an opioid analgesic used to relieve moderate to severe pain. Unfortunately, as with all opioids, chronic use of this drug can lead to Opana addiction. One formulation of the drug, Opana ER (oxymorphone hydrochloride), was even recently requested to be removed from the market by the FDA.11 Overcoming addiction can seem like a daunting task. However, finding an inpatient Opana rehab center can help you start on your road to recovery.

In this article:

What is Opana and How Addictive is It?

Opana (also known as oxymorphone) was first approved by the U. S. Food and Drug Administration (FDA) in 2006 as a pain management drug. The Opana pill works similarly to other opioid analgesics, attaching to the opioid receptors in your brain and blocking feelings of pain and discomfort. As with other opioids, Opana causes feelings of euphoria. Moreover, Opana can dissolve in fatty tissue and reach your brain quicker than other opioids.1 That means you feel the effects of Opana soon after taking it.

The makers of the drug tried to reformulate it in 2012. Their original formula showed a high frequency of Opana abuse among those who were prescribed it and misuse among persons taking the drug illicitly.2 However, in 2017, the FDA removed the reformulated version of Opana from the market. Their reasoning was that the benefits of the pain reliever did not outweigh the risks associated with increased opioid availability.2 Even though Opana is no longer allowed to be produced and sold, generic versions of the drug remain available.

Opana Pill Addiction

Chronic use of the drug can lead to Opana addiction. An Opana addiction is when you have a compulsive urge to use the drug after it is no longer medically required or if it harms you and consumes your time.3

Opana and other opioid drugs are very addictive. Misuse, however, is extremely common. It is estimated that three million Americans have had or currently have opioid use disorder.4 You can become addicted to opioids even if you take the medication as prescribed because it changes your brain chemistry.3 As you repeatedly seek pleasurable highs from the drug, your body develops a tolerance and dependence on it, which leads to more use and perpetuates the cycle of addiction.

What is an Inpatient Opana Rehab?

If you have an Opana addiction, finding treatment is essential to a full recovery. An inpatient opioid rehab is a helpful treatment option to begin your journey. Inpatient rehab means you will stay at a recovery center 24 hours a day for a period deemed necessary by your treatment team. Inpatient differs from outpatient programs in that you do not return home each night but instead reside at the rehab facility.

Treating Opana addiction, and other opioid use disorders, is unique to other addiction treatment plans in a few ways:5

  • Continuing care is required for an extended period rather than a one-time, acute treatment approach
  • Medications used to treat OUD can be used in the long term, even over a lifetime
  • Treatment medications do not just assist with alleviating withdrawal symptoms but also block the cravings and effects of opioid drugs, such as Opana

When you enter an inpatient Opana rehab, medical professionals will assess what level of care you need and create a treatment plan appropriate for your situation. Detox is likely to be the first step in this treatment plan, which involves medical management of any withdrawal symptoms.

A rehab center’s philosophy towards treatment will inform their approach. Some rehabs incorporate religion and spirituality into their care. Others may use holistic approaches in addition to standard medicines in their treatment. Many centers include research-based therapy modalities to treat your condition after detoxification has been completed.

Regardless of the type of center you visit, most inpatient Opana rehab treatment plans will include some or all of the following:4

  • Education about Opana addiction and other opioid use and how it impacts your health
  • Cognitive-behavioral therapy to help you identify unhealthy thinking and behaviors
  • Motivational therapy to help you change patterns and learn new coping skills
  • Support groups with others on a recovery journey
  • Opioid replacement, maintenance, or substitution therapy through medication
  • Medication to treat withdrawal symptoms

Medications Used in a Treatment Program

The Federal Drug Administration (FDA) has approved three medications that are safe and have been shown to reduce withdrawal symptoms. These enable you to recover from an Opana addiction while still functioning in your job, family, and social circles:6, 7, 8

  1. Methadone: This is a synthetic opioid agonist that eliminates withdrawal symptoms and relieves drug cravings without producing Opana’s euphoric effects. This is a long-term treatment medication and has been proven very effective at preventing relapse.
  2. Buprenorphine: This is a partial opioid agonist that also helps with withdrawal symptoms and cravings but has a less intense effect than methadone.

Naltrexone is not used to lessen withdrawal symptoms. However, it is used for detox and relapse prevention. It is an antagonist, meaning it attaches to the opioid receptors in the brain but does not activate them.

Benefits of Inpatient Care

You may wonder whether you will receive inpatient and outpatient care for your Opana addiction. This will be assessed as soon as you check in at the facility or through referral from your doctor. Outpatient care is normally used as a step down in treatment once you have finished inpatient care. With that being said, there are many benefits to inpatient care, including:

  • A highly structured care approach that provides comfort and consistency
  • Rigid routines that help you develop better habits and coping skills
  • Separation from an environment that may enable you to relapse
  • Little to no exposure to triggers or stressors that make you relapse into Opana abuse
  • 24-hour access to medical professionals
  • A safe place to detox and receive medication for withdrawal symptoms
  • Supportive community of people on the same recovery journey

Research also supports the benefits of inpatient care. One survey found that in a group of people with opioid addiction, 27% relapsed the day they left a brief detox program, and 65% relapsed within 30 days of leaving.9

Another study also found that learning new behaviors and making lasting habit changes is more successful when you also change your environment.10 Being in an inpatient environment where triggers and drug accessibility are removed gives you a better chance of making long-term changes to your lifestyle.

Do I Need Inpatient Rehab for Opana Addiction?

You may be wondering if inpatient Opana rehab is the right choice for you. While any treatment is better than no treatment, you should consider some things in deciding if you need inpatient care. Some of those considerations include:

  • If you are at a high risk of experiencing withdrawal symptoms once you stop using Opana
  • If you have experienced a relapse before
  • If you have tried a less intensive level of treatment but were unable to stay sober
  • If you do not have a good support system at home or in your social circles
  • If you have another condition alongside your Opana addiction, such as anxiety or depression
  • If you need structure and routine to recover

If you are still unsure about whether inpatient rehab is right for you, consult a healthcare professional to assess what level of care you need.

How to Choose Inpatient Rehab for Opana Addiction

You can choose from many inpatient Opana rehab programs. As you sort through the options available to you, you can ask yourself some helpful questions:

  • Does this center accept your insurance?
  • How much will care cost, and what are your payment options?
  • Where is the treatment center located?
  • What kind of recovery setting and environment do you want?
  • What are the accreditation and credentials of the center and its staff?
  • What does a typical day look like in recovery at this center?
  • What are the program rules and guidelines?
  • What amenities does the center offer?
  • Can family and friends visit you while in recovery?
  • What sort of follow-up care does the center offer once you leave?
  • How does the center incorporate spirituality or other preferences you may have?

If you or someone you love has an Opana addiction, please call 800-926-9037 (Info iconWho Answers?) to speak to a specialist about treatment options. They can help you learn about inpatient Opana treatment.


  1. Sloan, P. (2008). Review of oral oxymorphone in the management of pain. Therapeutics and clinical risk management, 4(4), 777-787.
  2. United States Food and Drug Administration. (2018). Oxymorphone (marketed as Opana ER) Information. United States Government.
  3. National Library of Medicine. (n.d.). Opioid addiction: MedlinePlus Genetics. U. S. Department of Health and Human Services National Institutes of Health.
  4. Dydyk, A. M., Jain, N. K., Gupta, M. (2022). Opioid Use Disorder. StatPearls Publishing.
  5. Substance Abuse and Mental Health Services Administration. (2018). Medications for Opioid Use Disorder: For Healthcare and Addiction Professionals, Policymakers, Patients, and Families. Treatment Improvement Protocol (TIP) Series, No. 63., Part 1, Introduction to Medications for Opioid Use Disorder Treatment.
  6. United States Food and Drug Administration. (2019). Information about Medication-Assisted Treatment (MAT). United States Government.
  7. National Institute on Drug Abuse. (2021). How do medications to treat opioid use disorder work?
  8. Centers for Disease Control. (n.d.). Module 5: Assessing and Addressing Opioid Use Disorder (OUD).
  9. Bailey, G. L., Herman, D. S., & Stein, M. D. (2013). Perceived Relapse Risk and Desire for Medication Assisted Treatment among Persons Seeking Inpatient Opiate Detoxification. Journal of Substance Abuse Treatment, 45(3), 302-305.
  10. Carden, L., & Wood, W. (2018). Habit formation and change. Current Opinion in Behavioral Sciences, 20, 117-122.
  11. United States Food and Drug Administration. (2017). FDA requests removal of Opana ER for risks related to abuse. [Press release].